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CECs, Centro de Estudios Científicos (Center for Scientific Studies) is a private, non-profit corporation, devoted to the development, promotion and diffusion of scientific research. CECs was founded in 1984 as the Center for Scientific Studies of Santiago and has since been directed by physicist Claudio Bunster.

“If you plan to make a voyage of discovery, choose a ship of small draught”
Captain James Cook rejecting the large ships offered by the Admiralty for the search of a new continent.
 
Biology

NEW EVIDENCE OF THE ROLE OF NITRIC OXIDE IN THE MODULATION OF ENERGETIC METABOLISM IN THE BRAIN

 

Researchers of the CECs Biology Lab contributed new evidence[1] that Nitric Oxide can modulate the energetic metabolism of astrocytes, cells in charge of basic aspects for the maintenance and neural function in the brain. The publication was one of the most noted[2] by the JOURNAL OF BIOLOGICAL CHEMISTRY’s editorial committee.  

 

ASN

 

A) Schematic representation of Laconic (LACtate Optical Nano-Indicator from CECs) used this study. B) Mammalian cells expressing Laconic in the cytosol. C) Modulation of the intracellular concentration of glucose by nitric oxide, an effect enhanced by low oxygen concentration. Signal detected with a fluorescent nanosensor for glucose expressed in astrocytes. Article’s original image.

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