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CECs, Centro de Estudios Científicos (Center for Scientific Studies) is a private, non-profit corporation, devoted to the development, promotion and diffusion of scientific research. CECs was founded in 1984 as the Center for Scientific Studies of Santiago and has since been directed by physicist Claudio Bunster.

“If you plan to make a voyage of discovery, choose a ship of small draught”
Captain James Cook rejecting the large ships offered by the Admiralty for the search of a new continent.
 
  

 

Not Just Neurology.

A NEW DIRECTION TOWARDS UNDERSTANDING RETT SYNDROME.

 

Researchers from the CECs Biology Lab have published the results of a study in the Molecular and Cellular Pediatrics Journal, which points to unraveling changes in the intestinal epithelium present in Rett Syndrome, a severe disorder of the central nervous system.

 

DIHQ Mecp2

 

To conduct the research, they decided to study phenotypical intestinal levels in mice with Mecp2-null gene and diarrhea present. The results show that silencing the Mecp2 gene significantly affects the colon. The changes in length and epithelial histology are similar to those seen in colitis, and the changes in protein localization that participate in the absorption of fluids could explain the diarrhea, but exclusive deletion of Mecp2 from the intestine did not reproduce colon changes observed in the MECP2-null mice, which suggests the participation of other cells in these phenotypes, indicating a more complex mechanism that just silencing the gene.

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